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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2077 | Adavosertib | AZD1775,MK-1775,Adavosertib (MK-1775) | Wee1 |
Adavosertib (MK-1775) is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint. | |||
T77496L | AZD 1775 Linker Conjugate 1 TFA | AZD 1775 Linker Conjugate 1 TFA( 2101954-45-2 Free base) | |
AZD 1775 Linker Conjugate 1 TFA is a compound involved in ubiquitinase-targeted chimeric assays | |||
T41163 | ZNL 02-096 | Pomalidomide-C3-adavosertib | Apoptosis , Wee1 |
ZNL 02-096 (Pomalidomide-C3-adavosertib) is a rapid and selective degrader of Wee1 (IC50=3.58 nM).ZNL 02-096 selectively degrades Wee1 at submolar concentrations without damaging PLK1, a secondary target of AZD 1775.ZNL ... |